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APOLIPOPROTEIN C-II
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DeCS
Descriptor
English
:
Apolipoprotein C-II
Descriptor
Spanish
:
apolipoproteína C-II
Descriptor
Portuguese
:
Apolipoproteína C-II
Synonyms
English
:
Apo C II
Apo C-II
ApoC2
Apolipoprotein C 2
Apolipoprotein C II
Apolipoprotein C-2
Apolipoprotein CII
Apoprotein C II
Apoprotein C-II
Tree Number:
D10.532.091.400.750
D12.776.070.400.400.750
D12.776.521.120.400.750
Definition
English
:
A 9-kDa protein component of VERY-LOW-DENSITY
LIPOPROTEINS
. It contains a cofactor for
LIPOPROTEIN LIPASE
and activates several triacylglycerol lipases. The
association
of Apo C-II with
plasma
CHYLOMICRONS
; VLDL, and HIGH-DENSITY
LIPOPROTEINS
is reversible and changes rapidly as a function of triglyceride
metabolism
. Clinically, Apo C-II deficiency is
similar
to
lipoprotein lipase
deficiency (
HYPERLIPOPROTEINEMIA TYPE I
) and is therefore called
hyperlipoproteinemia
type IB.
See Related
English
:
Hyperlipoproteinemia Type I
History Note
English
:
2007; use APOLIPOPROTEIN C-II (NM) 1978-2006
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52263
Unique Identifier:
D053304
Occurrence in VHL
:
Similar:
DeCS